WebChemotherapy-induced peripheral neuropathy (CIPN) is a major dose-limiting side effect of many commonly used chemotherapeutic agents, including platinum drugs, taxanes, epothilones, and vinca alkaloids, but also newer agents such as bortezomib and lenolidamide. Neurotoxic chemotherapeutic agents may cause structural damage to … WebThis is a list of chemotherapeutic agents, also known as cytotoxic agents or cytostatic drugs, that are known to be of use in chemotherapy for cancer.This list is organized by type of agent, although the subsections are not necessarily definitive and are subject to …
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WebOct 6, 1999 · Despite identified limitations in the grading and reporting of treatment-related anemia, which are evidenced in this review, the collective results confirm a relatively high incidence of mild-to-moderate anemia across the major nonmyeloid tumors treated with the most commonly used single agents and combination chemotherapy regimens. … WebPlatinum drugs are important components of multiagent chemotherapy regimens for numerous malignancies, including sarcomas, and tumors of the testes, ovary, bladder, lung, brain, head and neck, and others (Kelland, 2007). Cisplatin is known to produce … forest closures new mexico
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The first platinum-based chemotherapy drug, cisplatin, was approved for use by the FDA in 1978Trusted Source. Researchers are continuing to examine newer drugs that may cause fewer side effects. See more Platinum-based chemotherapy drugs can cause serious complications, such as cognitive changes or cardiovascular problems. Your doctor may recommend lowering your dose or stopping treatment if you develop severe … See more Researchers are continuing to examine whether platinum-based chemotherapy is safe for people who are pregnant or breastfeeding. In a small 2024 study, researchers found evidence that it might be reasonably safe … See more According to the American Cancer SocietyTrusted Source, it’s generally not recommended to receive a vaccine during chemotherapy or radiation treatment. The exception is the flu … See more A dose-limiting side effect is a side effect that’s serious enough to prevent doctors from increasing the dose of the drug further. The dose-limiting side effect of cisplatin is nephrotoxicity, the deterioration of your kidney … See more WebSep 22, 2010 · Based on the BRCA1 dysfunction phenotype of BLBC, one approach has been the exploration of platinum chemotherapy agents (carboplatin, cisplatin, and others) in these patients. Platinum agents produce DNA cross-links, which lead to DNA double-strand breaks, normally repaired by BRCA½-mediated high-fidelity homologous … WebDec 21, 2024 · Platinum (Pt) agents, usually referring to carboplatin (Cb) and cisplatin(DDP), are cytotoxic DNA-damaging chemo-drugs widely used in various malignancies. Platinum can cause DNA strand breaks ... forest cmc