Ctdnatools
WebToggle navigation ctDNAtools 0.4.0. Get started; Reference; Changelog; Reference. Minimal Residual Disease testing. test_ctDNA() Tests the ctDNA positivity of a sample. create_background_panel() Creates a background panel from a list of bam files. create_black_list() WebA function to extract fragment lengths from a bam file. Optionally, given a mutation data frame, it can categorize read lengths in mutated vs non-mutated reads.
Ctdnatools
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WebMar 26, 2024 · In ctDNAtools: Analyze Circulating Tumor DNA Sequencing Data. Description Usage Arguments Details Value See Also Examples. View source: … WebR package to work with ctDNA sequencing data. Contribute to alkodsi/ctDNAtools development by creating an account on GitHub.
WebToggle navigation ctDNAtools 0.4.0. Get started; Reference; Changelog; Collapses mutations in phase into one event Source: R/merge_mutations_in_phase.R. merge_mutations_in_phase.Rd. Given a mutations data frame and a bam file, this function collapses mutations in phase identified by the ID_column into one event. While doing … WebJan 28, 2024 · The ctDNAtools R package is presented, which provides functionalities for testing minimal residual disease (MRD) and analyzing cfDNA fragmentation and includes …
WebMar 26, 2024 · ctDNAtools: Analyze Circulating Tumor DNA Sequencing Data. Contains tools to analyze minimal residual disease and cell-free DNA fragmentation from aligned … WebCirculating tumor DNA fraction prediction Metastatic castration-resistant prostate cancer
WebctDNAtools (version 0.4.0) create_black_list: Creates a black list of genomic loci based on a background panel created from a list of bam files (e.g. healthy samples) Description
WebJan 27, 2024 · Here, we present the ctDNAtools R package, which provides functionalities for testing minimal residual disease (MRD) and analyzing cfDNA fragmentation. MRD … fish in hiraganaWebR package to work with ctDNA sequencing data. Contribute to alkodsi/ctDNAtools development by creating an account on GitHub. can chemotherapy cause depression and anxietyWebMar 26, 2024 · mutations: Example mutations data to use with ctDNAtools package; positivity_test: Computes a p-value of ctDNA positivity with a Monte-Carlo... simulator: A function to sample from binomial distribution; summarize_fragment_size: Summarizes fragment size in defined genomic regions; targets: Example Genomic targets to use with … fishin hole calgaryWebJan 28, 2024 · Here, we present the ctDNAtools R package, which provides functionalities for testing minimal residual disease (MRD) and analyzing cfDNA fragmentation. MRD … can chemotherapy cause hyperglycemiaWebJan 27, 2024 · Additionally, ctDNAtools includes various functionalities to study cfDNA fragment size histograms, profiles and fragment ends patterns. Availability: The … fish in high rock lake ncWebTests the ctDNA positivity of a sample. Source: R/test_ctDNA.R. Given a set of reporter mutation, this functions counts the reads matching the reporter mutations in the sample to be tested, estimates the mismatch rate for the sample to be tested, and then runs a Monte Carlo simulation test to determine whether the tested sample is positive or ... fish in hindiWebHere, we present the ctDNAtools R package, which provides functionalities for testing minimal residual disease (MRD) and analyzing cfDNA fragmentation. MRD detection in ctDNAtools utilizes a Monte Carlo sampling approach to test ctDNA positivity through tracking a set of pre-detected reporter mutations in follow-up samples. can chemotherapy cause hypothyroidism