Ctsb abcam
WebDec 17, 2024 · CTSB regulates the anticancer activity of sorafenib in vivo We next focused on sorafenib, which is a clinically approved multikinase inhibitor that can trigger ferroptosis in various cancer cells. WebFeb 20, 2016 · CTSB, composed of a heavy chain of 25–26 kDa and a light chain of 5 kDa, belongs to a family of lysosomal cysteine proteases and plays an important role in intracellular proteolysis [ 14 ]. Numerous studies have shown that overexpression of CTSB is correlated with invasive and metastatic cancers.
Ctsb abcam
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WebAbcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that … WebMar 23, 2024 · Thus, we conclude that both Ctsb and Ctsd deficiency caused impaired autophagy in the pancreatic acinar cells, and induced CP in mice. Autophagy is a system of intracellular degradation that...
WebWhen CTSB release was monitored by indirect immunofluorescence using an automated confocal imaging approach, we found a subcellular redistribution of lysosomal CTSB into discrete cytoplasmic dots (in b) that markedly increased 6 h after treatment with CQ (60 μM) compared to control cells (Figure 2C).
WebDec 28, 2024 · Cathepsin B (CTSB), a papain-family cysteine protease, performs distinct functions and executes independent mechanisms based on diverse isoforms and … WebAbcam ctsb Ctsb, supplied by Abcam, used in various techniques. Bioz Stars score: 86/100, based on 16 PubMed citations. ZERO BIAS - scores, article reviews, protocol …
WebOct 10, 2024 · Cathepsin B (CTSB) or OGT deficiency in M2-like macrophages impaired the protective effect of M2-like macrophages on tumor cell death in response to paclitaxel or oxaliplatin treatment, ... Abcam: Cat#ab125069; RRID: AB_10975709: Phospho-Stat6 (Tyr641) Antibody: Cell Signaling Technology: Cat#9361; RRID: AB_331595: Mouse …
WebAntibodies to CTSB (Abcam), CTSD (Epitomics), and β-actin (Sigma) were used. After incubation with primary antibody, membranes were washed in TBST 3 times and then incubated with specific secondary antibodies (Zhongshan Golden Bridge Biotechnology Co., Ltd.) in 5% skim milk for 2 h at room temperature. cincinnati men\u0027s basketball head coachWebGeneral notes. This product has switched from ascites to TCS on 26th October 2024. The Life Science industry has been in the grips of a reproducibility crisis for a number of … dhs office lincoln ilWebApr 24, 2024 · To detect the enzymatic activity of CTSB, the fluorescence signal was measured using a fluorometer (Gemini EM, Molecular Devices, San Jose, CA, USA) after cleavage of the specific substrate for... dhs office locations memphis tnWebAbcam ctsb activity assay kit fluorometric Ctsb Activity Assay Kit Fluorometric, supplied by Abcam, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed … dhs office lawton oklahomaWebCathepsins B, D, and G Are Expressed in Metastatic Head and Neck Cutaneous Squamous Cell Carcinoma. In Frontiers in Oncology on 9 October 2024 by Humphries, F., Chang … dhs office lonoke arWebThis product is manufactured by BioVision, an Abcam company and was previously called K147 Cathepsin B (CTSB) Inhibitor Screening Kit (Fluorometric). K147-100 is the same … dhs office knoxville tn middlebrookWebDec 28, 2024 · Protein biomarkers in serum samples were validated using Enzyme-Linked Immunosorbent Assay (ELISA) kits, including CTSB (Abcam, UK), vWF (Abcam, UK), C9 (Abcam, UK), DKK3 (R&D Systems, USA), MFGE8 (R&D Systems, USA), APOA2 (Abcam, UK), FABP4 (R&D Systems, USA), DES (RayBiotech, USA). cincinnati men\u0027s basketball team