WebbMoreover, silencing of PHLPP2 and FOXO4 mimicked the tumor-promotive effects of miR-762 on HNSCC cells. Notably, overexpression of PHLPP2 and FOXO4 abolished the pro-tumoral function of miR-762 on cell proliferation and migration. Conclusion: miR-762 promotes HNSCC progression by targeting PHLPP2 and FOXO4. WebbPHLPP2 is regulated by competing endogenous RNA network in pathogenesis of colon cancer Hong-Kun Wu1,*, Chang Liu1,*, Xin-Xing Li2,*, Wei Ji1, Chen-De Xin1, Zhi-Qian …
Cell atlas - PHLPP2 - The Human Protein Atlas
Webb1 dec. 2024 · Interestingly, PHLPP2 inhibition mediated by small interfering RNA (siRNA) knockdown significantly improved cell viability and downregulated apoptosis and … Webb4 feb. 2024 · Bladder cancer is one of the most common malignancies of the urinary tract and can be divided into non-muscle-invasive bladder cancer (NMIBC) and muscle … hampton inn scranton pa
PHLPP2 is a novel biomarker and epigenetic target for the …
WebbFor example, MIR2911, a plant 26S ribosomal RNA-derived small RNA, exhibited high stability against RNases and strong stability in circulation[Citation 150]. However, many … WebbPHLPP2 deletion in mouse endothelium results in decreased neo-intima formation following vascular injury, indicating that the prevention of AKT1 overactivation by … WebbThey are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing. For … burtons menswear leeds west yorkshire