WebDec 3, 2024 · However, the mechanism underlying PS externalization in renal tubule cells caused by CaOx-mediated damage remains unclear. ... Li YF, Yu SL, Gan XG et al (2024) MRP-1 and BCRP promote the externalization of phosphatidylserine in oxalate-treated renal epithelial cells: Implications for calcium oxalate urolithiasis. Urology 7:271.e9-271.e17 WebDec 19, 2024 · New types of alcohol-soluble phosphatidylserine (PS) derivatives are designed as materials that target immune cells and then incorporated into LNPs using a microfluidic technique with a high degree of scalability and reproducibility. The resulting LNP that contained the synthesized PS delivered mRNA to the spleen much more efficiently …
Delivering mRNA to Secondary Lymphoid Tissues by Phosphatidylserine …
WebAug 3, 2024 · We reveal that Myomerger is regulated by movement of phosphatidylserine (PS) to the outer leaflet of membranes, which links a well-known fusion-associated phenomenon (PS externalization) to the myogenic fusion reaction. We propose that externalized PS acts as a trigger to enhance the membrane-destabilizing activity of … WebPhosphatidylserine (PS) is the major acidic phospholipid class that accounts for 13–15% of the phospholipids in the human cerebral cortex.[6] In the plasma membrane, PS is localized exclusively in the cytoplasmic … ions tartrates
The RGD finger of Del-1 is a unique structural feature critical …
WebAug 17, 2024 · Here, we show that exposed phosphatidylserine (PS) represents a neuronal "eat-me" signal involved in microglial-mediated pruning. In hippocampal neuron and … WebApr 11, 2024 · CD8 + T cells are crucial for the clearance of viral infections. During the acute phase, proinflammatory conditions increase the amount of circulating phosphatidylserine + (PS) extracellular vesicles (EVs). These EVs interact especially with CD8 + T cells; however, it remains unclear whether they can actively modulate CD8 + T cell responses. In this study, … ion std 101